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Senior MSAT Engineer

Indianapolis $100,000 - $120,000 Permanent

Responsibilities

  • Serve as a technical subject matter expert (SME) for commercial and clinical manufacturing processes, ensuring reliable and compliant production performance.

  • Lead process troubleshooting, deviation investigations, and root cause analyses for upstream, downstream, or fill-finish operations.

  • Support technology transfer of new products and processes from development to manufacturing sites, including documentation and scale-up activities.

  • Author and review process descriptions, batch records, risk assessments, and change controls in alignment with cGMP requirements.

  • Collaborate with Quality, Validation, and Engineering teams to implement process improvements and corrective/preventive actions (CAPAs).

  • Monitor and trend process performance data (yields, deviations, cycle times, etc.) to identify improvement opportunities and ensure control state.

  • Provide technical support during regulatory inspections, audits, and process validation activities.

  • Partner with R&D and Process Development to optimize and characterize critical process parameters and ensure smooth handoffs to manufacturing.

  • Lead and mentor junior engineers or specialists within the MSAT team.

Qualifications

  • Bachelor’s or Master’s degree in Chemical Engineering, Biochemical Engineering, or related life sciences discipline.

  • 5–10 years of experience in pharmaceutical, biotech, or CDMO manufacturing support (drug substance, drug product, or aseptic operations).

  • Strong working knowledge of GMP manufacturing principles, process validation, and technology transfer.

  • Hands-on experience with bioreactors, filtration systems, chromatography skids, or fill-finish equipment, depending on area of focus.

  • Demonstrated ability to analyze complex process data, identify root causes, and drive improvements.

  • Experience supporting deviation investigations, CAPA, and change control systems.

  • Excellent technical writing, communication, and cross-functional collaboration skills.

  • Familiarity with process automation systems (DeltaV, Rockwell, or equivalent) and data trending tools preferred.

  • Continuous improvement, Six Sigma, or statistical analysis experience is a plus.

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